Table 1.

The prior distribution p(θ) of the model parameters $\mathit{\theta }=\{\alpha ,T_{1b},T_{1t},{\tau }_{\mathrm{trans}},{\tau }_a,V_c,V_v,\mathrm{\Delta }t,t_0\}$ in GM in the general population

	Parameter	Parameter distribution
Parameters	labeling efficiency α [ ]	$\mathcal{N}(0.80,0.06)$ [39, 40]
	longitudinal relaxation time of blood $T_{1b}$ [s]	$\mathcal{N}(1.65,0.12)$ [7, 8, 41]
Specific IRF parameters	longitudinal relaxation time of tissue $T_{1t}$ [s]	$\mathcal{N}(1.45,0.14)$ [29]
	blood‐to‐tissue water transit time ${\tau }_{\mathrm{trans}}$ [s]	$\mathcal{U}(0.30,3.60)$ [42, 43, 44]
	arterial microvascular transit time ${\tau }_a$ [s]	$\mathcal{U}(0.30,1.00)$ [45, 46, 47]
	tracer capillary distribution volume $V_c$ [mL/100g]	$\mathcal{U}(2.0,4.0)$ [37, 48]
	tracer venous distribution volume $V_v$ [mL/100 g]	$\mathcal{U}(1.0,3.0)$ [49, 50]
Specific AIF parameters	arterial transit time Δt [s]	$\mathcal{N}(0.82,0.15)$ [12, 13]
	center‐of‐vessel travel time $t_0$ [s]	$\mathcal{N}(0.10,0.01)$ [21, 22]

Note: A normal distribution is described as $\mathcal{N}(\mu ,\sigma )$ with μ the mean and σ the standard deviation; a uniform distribution is described as $\mathcal{U}(l,u)$ with l and u the lower and upper bound, respectively.