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. 2020 May 7;84(5):2739–2753. doi: 10.1002/mrm.28303

Figure 3.

Figure 3

Spherical Mean Technique (SMT) 20 , 21 for microscopic diffusion anisotropy mapping. (a) Estimation of microscopic diffusion features, such as microscopic fractional anisotropy and intra‐axonal volume fraction, unconfounded by fiber crossings and orientation dispersion. (b) Quantitative recovery of the axon orientation distribution using spherical deconvolution with a spatially varying impulse response function, showing the crossing of the callosal fibers and the pyramidal tract in the centrum semiovale. (c) Probabilistic tractography, 48 visualized with MRtrix3, revealing the complex architecture of the fiber pathways in the individual human brain