Table 2.
Effect of treatment on the primary outcome variables: biomarkers of oxidative stress.
| ERW (n = 29) |
MW (n = 24) |
p | |||
|---|---|---|---|---|---|
| Outcome Variables | Means ±SD | Means ±SD | Time | Group | Time * Group |
| d-ROMs(U.CARR) | |||||
| Baseline | 301.3 ± 68.6 | 347.3 ± 94.9 | |||
| 4 weeks | 286.7 ± 45.1 | 306.3 ± 54.8 | 0.004 | 0.007 | 0.044 |
| 8 weeks | 288.0 ± 50.0 | 349.6 ± 62.7 | |||
| BAP (umol/L) | |||||
| Baseline | 2027.4 ± 226.9 | 2015.7 ± 274.8 | |||
| 4 weeks | 2585.9 ± 258.8 | 2504.8 ± 187.8 | 0.000 | 0.875 | 0.045 |
| 8 weeks | 2603.9 ± 255.9 | 2670.4 ± 180.2 | |||
| TBARS (MDA) (μM) | |||||
| Baseline | 9.88 ± 4.67 | 8.90 ± 5.98 | |||
| 4 weeks | 6.84 ± 3.99 | 8.95 ± 6.14 | 0.003 | 0.809 | 0.091 |
| 8 weeks | 6.97 ± 4.51 | 6.63 ± 4.47 | |||
| 8-OHdG (ng/mL) | |||||
| Baseline | 14.33 ± 6.88 | 10.90 ± 6.42 | |||
| 4 weeks | 13.87 ± 8.31 | 15.63 ± 11.18 | 0.033 | 0.594 | 0.138 |
| 8 weeks | 11.87 ± 7.90 | 10.87 ± 7.00 | |||
| oxLDL (U/L) | |||||
| Baseline | 52.43 ± 17.38 | 49.38 ± 13.61 | |||
| 4 weeks | 53.60 ± 15.32 | 52.00 ± 12.94 | 0.332 | 0.679 | 0.534 |
| 8 weeks | 52.24 ± 15.97 | 52.1 ± 12.99 | |||
| GPx (nmol/min/mL) | |||||
| Baseline | 151.4 ± 31.1 | 140.1 ± 34.9 | |||
| 4 weeks | 162.8 ± 36.5 | 161.7 ± 37.9 | 0.000 | 0.639 | 0.412 |
| 8 weeks | 185.8 ± 30.9 | 189.6 ± 23.6 | |||
Note: * Interaction between Time and the Group. Abbreviations: ANOVA, analysis of variance; d-ROMs, diacron-reactive oxygen metabolites; BAP, biological antioxidant potential; TBARS, thiobarbituric acid reactive substances; MDA, malondialdehyde; 8-OHdG, 8-hydroxy-2-desoxyguanosine; oxLDL, oxidized low-density lipoprotein; GPx, glutathione peroxidase.