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. 2020 Jul 18;9(7):637. doi: 10.3390/antiox9070637

Table 1.

Protective effects of plant-derived extracts against ultraviolet (UV) radiation-induced toxicity.

Models Materials Key Findings Literature
C57BL/6 mice, SKH-1 hairless mice Sasa quelpaertensis Topically applied plant extracts reduced edema and erythema in mice exposed to UV light. [76]
SKH:hr-1 hairless albino mice Propolis The extract reduced cutaneous inflammation, immunosuppression, and lipid peroxidation induced by UV exposure. [77]
SKH-1 hairless mice Broccoli sprout Dietary glucoraphanin-rich broccoli sprout extracts protected against UV-induced skin carcinogenesis. [78]
Primary keratinocytes Blackberry Anthocyanin-rich fractions of blackberry extracts reduced UV-induced free radicals and oxidative damage in cells. [79]
HaCaT human keratinocytes Gardenia jasminoides The extract displayed antioxidant, anti-inflammatory, and anti-apoptotic effects. [41]
Human epidermal keratinocytes, Human dermal fibroblasts Portulaca oleracea The extracts protected human keratinocytes and fibroblasts from UV-induced apoptosis. [80]
HaCaT human keratinocytes, Human volunteers Citrus and Rosemary The extracts protected UV-induced damage in a skin cell model and in human volunteers. [81]
HaCaT human keratinocytes Bambusae caulis in Taeniam The extract enhanced the viabilities of UVB-exposed cells and reduced the number of apoptotic events. [42]
HaCaT human keratinocytes, Humans volunteers Scutellaria radix The extract enhanced the sun protection factor (SPF) of a sunscreen product, as determined in human subjects. [82]
HaCaT human keratinocytes, Reconstituted human skin tissue Propolis The extract inhibited UV-induced photodamage. [83]