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. 2020 Jul 18;9(7):637. doi: 10.3390/antiox9070637

Table 2.

Cytoprotective effects of plant-derived antioxidants in melanocytes.

Materials Models Key Findings Literature
Quercetin
Inline graphic 		Mel-Ab melanocytes Quercetin reduced H2O2-induced cell death. [107]
Normal human epidermal melanocytes Quercetin attenuated ER dilation and H2O2-induced apoptosis. [108]
Apigenin
Inline graphic 		Normal human epidermal melanocytes Apigenin attenuated dopamine-induced apoptosis. [109]
Hyperoside
Inline graphic 		Normal human epidermal melanocytes Hyperoside (quercetin-3-O-galactoside) decreased apoptosis of H2O2-injured melanocytes. [110]
(−)-Epigallocatechin-3-gallate
Inline graphic 		Normal human epidermal melanocytes (−)-Epigallocatechin-3-gallate decreased apoptosis in H2O2-injured melanocytes. [111]
Afzelin
Inline graphic 		Normal human epidermal melanocytes Afzelin (kaempferol-3-O-rhamnoside) inhibited H2O2-mediated cell death. [112]
Baicalein
Inline graphic 		Human vitiligo melanocytes Baicalein inhibited H2O2-induced cytotoxicity and apoptosis. [113]
Geniposide
Inline graphic 		Normal human epidermal melanocytes Geniposide (genipin-1-O-glucoside) decreased the apoptosis rate of H2O2-treated cells. [114]
Bilobalide
Inline graphic 		Normal human epidermal melanocytes Bilobalide attenuated H2O2-induced apoptosis and ER stress. [115]