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. 2020 Jul 4;9(7):585. doi: 10.3390/antiox9070585

Figure 2.

Figure 2

SPA0355 ameliorated renal dysfunction in mice treated with lipopolysaccharide (LPS). Mice were treated with a single intraperitoneal injection of SPA0355 (50 mg/kg body weight in corn oil) 1 h before administration of LPS (10 mg/kg body weight). (A) Plasma levels of creatinine. (B) Plasma levels of blood urea nitrogen (BUN). Results are from 8 mice per group (biological replicates) and 2 technical replicates per mouse. *** p < 0.001 vs. vehicle-treated mice (Veh). ### p < 0.001 vs. LPS-injected mice (LPS).