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SPA0355 prevented immune cell infiltration into damaged kidneys and inhibited NF-κB activation. (A) Representative images of IHC of Mac-2 or CD4 in kidneys. Red arrows indicate positively stained cells. Bar = 20 μm. (B) Number of Mac-2-positive cells. (C) Number of CD4-positive cells. Results are from 8 mice per group (biological replicates) and 2 technical replicates per mouse. *** p < 0.001 vs. vehicle-treated mice (Veh). ### p <0.001 vs. LPS-treated mice (LPS).
