Table 1.

Frequency of mutations of genes encoding elements of the canonical WNT-signaling pathway detected in melanoma.

Gene	Literature Data		Melanoma (cbioportal.org; 1284 Cases)
APC	15%	[74]	10.0%
	11%	[79]
	2.7%	[73]
AXIN1	–		2.9%
AXIN2	11%	[79]	1.3%
BCL9	–		5.7%
CTNNB1	23%	[68]	5.9%
	4.6%	[71]
	3.3%	[71]
	11%	[79]
	1.6%	[72]
	1.5%	[69]
	5.4%	[73]
	3.2%	[70]
	3.7%	[70]
FBXW7	8.1%	[80]	3.4%
	8.3%	[81]
GSK3β	–		1.2%
SFRP	–		1.7%
WIF1	–		2.8%