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(A) Cytotoxicity of TiO2 NP (24 h exposure) to NR8383 by WST-1 test and (B) loss of membrane integrity by LDH release measurement. Non exposed cells are negative control (C−) and positive control (C+) for LDH are cells exposed to the lysis buffer (Triton 5%) during 15 min before the measure. Data are presented as means ± standard deviation (SD) of the four biologic replicates.
