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. 2020 Jun 23;91(8):814–821. doi: 10.1136/jnnp-2019-322636

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Group differences in right amygdala–MFG connectivity between T carriers, GG homozygotes and HCs. Mean z-scores were extracted for the right amygdala–MFG rsFC cluster. Post hoc two-sample t-tests indicated that patients with FMD carrying the T allele (PAT_TX) exhibited reduced right amygdala–right MFG functional connectivity when compared with GG carriers (PAT_GG) (t=3.61, df=39, p=0.0009) and HCs (t=3.803, df=48, p=0.0004), who both exhibited increased connectivity between these regions. Sample size: 38 patients with FMD and 38 age-matched and gender-matched HCs. FMD, functional movement disorder; HC, healthy control; MFG, middle frontal gyrus; rsFC, resting-state functional connectivity. **P ≤ 0.01