Table 2. Description of selected studies on metabolic effects.

p-REBOA: partial resuscitative endovascular balloon occlusion of the aorta; c-REBOA: complete resuscitative endovascular balloon occlusion of the aorta; ARDS: acute respiratory distress syndrome; IL-6: interleukin-6

Study	Year	Number of patients	Conclusion
Kauvar et al. [33]	2019	21 swine	Higher lactate levels in c-REBOA that remained elevated in comparison to p-REBOA
Forte et al. [28]	2019	25 swine	Lactate levels increased with decreased perfusion. Comparison of flow rate with lactate levels are as follows: 0.7 L/min = 9.6 mmol/L; 0.5 L/min = 12.6 mmol/L, 0.3 L/min = 13.3 mmol/L
Sadeghi et al. [10]	2020	24 swine	Severe systemic metabolic disturbances, organ damage and inflammatory activation seen within 30 minutes of c-REBOA
Sadeghi et al. [31]	2018	18 swine	Elevated lactate and troponin in c-REBOA when compared to the control group and p-REBOA. Cytokine response and histologic changes more pronounced in c-REBOA
Morrison et al. [18]	2014	20 swine	Significant increase in IL-6 in the 60- and 90-minute complete occlusion groups. ARDS seen in all subject groups (30-, 60-, and 90-minute groups)