Table 1.
Comparison of spleen weight, WBC count and B/B + T lymphocyte ratio in Eµ-PKCβIItg and wt control mice.
| Wild type | Std | Eµ-PKCβIItg | Std | P value | |
|---|---|---|---|---|---|
| Spleen weight (mg) |
129.4 n = 7 |
9.02 |
120.4 n = 9 |
5.9 | 0.63 |
| WBC count (× 106 per ml) |
3.02 n = 7 |
0.78 |
3.74 n = 11 |
0.62 | 0.41 |
| B cell/B + T cells | |||||
| Spleen |
0.60 n = 10 |
0.046 |
0.73 n = 13 |
0.064 | 0.024 |
| Peritoneum |
0.85 n = 6 |
0.014 |
0.87 n = 10 |
0.024 | 0.25 |
| Peripheral blood |
0.71 n = 4 |
0.063 |
0.65 n = 10 |
0.052 | 0.44 |
B/B + T lymphocyte ratio in spleen, peritoneum and peripheral blood were determined using a FACS-based protocol identifying B cells (B220+CD5− live lymphocytes) and T cells (B220−CD5+ live lymphocytes). Statistical analysis was performed using a Mann–Whitney U-test.