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Renal histopathological changes (hematoxylin and eosin (HE) stain). A marked enlargement of the renal tubular lumen, renal tubular atrophy, mononuclear lymphocyte infiltration, and interstitial fibrosis in 5/6Nx compared with Sham group; while these histopathological changes were improved by rheum palmatum L enema treatment. Magnifications × 100.
