FIGURE 3.

Hierarchical clustering and principal component analysis (PCA) of the vascular endothelial cell (VEC) samples. (A) The expression patterns of all samples are shown in the heatmap. The sample numbers of the normal VECs (NVECs) and keloid VECs (KVECs) are indicated at the top. On hierarchical clustering, the KVECs and NVECs generally fell into two separate clusters. (B) PCA plots that visualize the distribution of KVECs and NVECs in terms of gene expression pattern. The KVECs were distributed close to each other and away from the NVECs. As a result, the KVECs could be divided from the NVECs by the indicated green broken line. The upper and lower plots indicate the distributions from two different 3-dimensional viewpoints.