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. 2020 Jul 29;8:658. doi: 10.3389/fcell.2020.00658

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Copyright © 2020 Matsumoto, Aoki, Okubo, Kuwahara, Eura, Dohi, Akaishi and Ogawa.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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In vitro study on the biological functions of SERPINA3 and LAMC2 in vascular endothelial cells and fibroblasts. (A) A human dermal vascular endothelial cell line (HMEC-1) was treated with or without 1 μg/ml lipopolysaccharide (LPS) for 15 h (n = 6). The relative mRNA expression levels of SERPINA3 and LAMC2 in the cells was determined. (B) Normal human dermal fibroblasts (NHDF) were treated with or without 0.5 μg/ml laminin-5 for 15 h (n = 10). The relative cell proliferation and apoptosis was measured. All values in this figure represent the mean ± SD. ** p < 0.01.