Table 1.

Comparison of the US Food and Drug Administration (FDA) Labeling for Mifepristone Followed by Misoprostol 2000 vs. 2016

	Original FDA-approved regimen (2000)	Updated FDA-approved regimen (2016)
Gestational age limits	49 days’ gestation	70 days’ gestation
Mifepristone dose and administration	600 mg on day 1 in clinic	200 mg on day 1 in clinic
Misoprostol dose and administration	400 mcg orally in clinic on day 3 post-mifepristone	800 mcg buccally at home 24–48 h post-mifepristone
Timing of follow-up assessment	7–14 days post-mifepristone	7–14 days post-mifepristone
Location of follow-up assessment	In clinic required	In clinic not required