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. 2020 Aug 4;10:13147. doi: 10.1038/s41598-020-69695-4

Table 2.

The enriched GO terms for the up-regulated DEGs of DSS and MPTP vs control, respectively.

GO Term Description Corrected p-value DEGs count
DSS vs control
GO:0098869 Cellular oxidant detoxification 1.08E−04 6
GO:1990748 Cellular detoxification 1.10E−04 6
GO:0098754 Detoxification 1.44E−04 6
GO:0097237 Cellular response to toxic substance 1.00E−03 7
GO:0015893 Drug transport 2.71E−03 6
GO:0002376 Immune system process 8.49E−03 17
GO:0042493 Response to drug 3.23E−02 10
GO:0030097 Hemopoiesis 3.23E−02 9
GO:0046501 Protoporphyrinogen IX metabolic process 3.23E−02 2
GO:0048534 Hematopoietic or lymphoid organ development 4.23E−02 9
MPTP vs control
GO:0035966 Response to topologically incorrect protein 7.61E−09 11
GO:0006986 Response to unfolded protein 1.67E−06 10
GO:0035967 Cellular response to topologically incorrect protein 6.57E−05 8
GO:0034620 Cellular response to unfolded protein 2.64E−04 7
GO:0030968 Endoplasmic reticulum unfolded protein response 1.55E−03 6
GO:0034976 Response to endoplasmic reticulum stress 6.22E−03 9
GO:0002376 Immune system process 2.88E−02 31
GO:2001234 Negative regulation of apoptotic signaling pathway 3.29E−02 8
GO:1904761 Negative regulation of myofibroblast differentiation 3.31E−02 2
GO:1903573 Negative regulation of response to endoplasmic reticulum stress 4.80E−02 4