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. 2020 Aug 4;10:13108. doi: 10.1038/s41598-020-69809-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of BPA on the expression of COX-2 and L-PGDS in the prostate. (a) Immunohistochemical images of COX-2 in the dorsolateral prostate and L-PGDS in the ventral prostate; Effect of BPA on COX-2 (b) and L-PGDS (c) expression in the prostate. (Scale bar = 50 µm, magnification × 200, n = 4). The protein bands of COX-2 and L-PGDS (d); The expression levels of the COX-2 protein in the dorsolateral prostate (e) and L-PGDS protein in the ventral prostate (f). Blots (d) were cropped from the gel presented in Supplementary Fig. 1. Bands were quantified using densitometry, with the results normalized to GAPDH expression in each sample (n = 3). Values are presented as mean ± SD (*P < 0.05, **P < 0.01, compared to the control).