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. 2020 Aug 4;7:253. doi: 10.1038/s41597-020-00592-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Quality check of BeadChip gene expression data of PcAS spleen samples.(a) Box plot showing distribution of 3,000 randomly sampled probe signals for normalised PcAS spleen expression data. The median, two hinges, two whiskers and outlying points were shown. (b) Principal component analysis of normalised expression data of naïve and infected spleen samples. (c) Hierarchical clustering plot of normalised intensity data among the samples was generated using agglomerative clustering with average linkage. (d) Heatmap of Euclidean distance. A full feature set was used for (b-d). This dataset was submitted to GEO (GSE123391).