Table 1.
Statistical parameters and detailed endoscopic findings.
| White-light endoscopy | Ce6-PVP-based endoscopy | |||
|---|---|---|---|---|
| Detection rate | 75% (6/8) | 100% (8/8) | ||
| Positive predictive value | 55% (6/11) | 19% (8/42) | ||
| False discovery rate | 45% (5/11) | 81% (34/42) |
| White-Light | Fluorescence | Histology | Histopathological diagnosis | |
|---|---|---|---|---|
| Mouse 1 | 1 | 3 | 0 | |
| Mouse 2 | 0 | 2 | 0 | |
| Mouse 3 | 0 | 3 | 0 | |
| Mouse 4 | 0 | 1 | 0 | |
| Mouse 5 | 1 | 2 | 0 | |
| Mouse 6 | 1 | 1 | 0 | |
| Mouse 7 | 2 | 5 | 2 | 2 Carcinomas |
| Mouse 8 | 4 | 11 | 3 | 3 High-grade dysplasias |
| Mouse 9 | 2 | 8 | 2 | 2 High-grade dysplasias |
| Mouse 10 | 0 | 6 | 1 | 1 High-grade dysplasia |
| Total | 11 | 42 | 8 |
Upper part: Cumulative statistical analysis of all detected lesions per modality (white-light or Ce6-PVP-based endoscopy) based on histologically confirmed lesions. Lower part: Detailed overview of detected lesions in each modality per mouse including the histopathological diagnosis and summary of the total number of lesions detected in each modality.