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. 2020 Jul 29;11:1036. doi: 10.3389/fphar.2020.01036

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Copyright © 2020 Liu, Piao, Niu, Zhang, Ma, Wu, Gu, Cui and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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HPLC analysis of serum chemicals. The chemicals (sulfasalazine, paeoniflorin and baicalin) were determined according to the standards in Figure 1A . All rats were divided into seven groups, the vehicle (CG), UG (UG, UC model), sulfasalazine (SG, sulfasalazine treatment), low-dose KD (LG, 20 mg/kg daily), middle-dose KD (MG, 40 mg/kg) and high-dose KD (HG, 80 mg/kg) groups. 1, gallic acid. 2, paeoniflorin. 3, emodin. 4, berberine. 5, coptisine. 6, palmatine. 7, jatrorrhizine. 8, baicalein. 9, baicalin.