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. 2020 Jul 29;11:1036. doi: 10.3389/fphar.2020.01036

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Copyright © 2020 Liu, Piao, Niu, Zhang, Ma, Wu, Gu, Cui and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effects of Kuijieyuan decoction on the expression of TLR4-dependent PI3K/AKT/NF-κB. (A) immunohistochemical analysis of TLR4 in the colon tissues. (B) immunohistochemical analysis of p-P3IK in the colon tissues. (C) immunohistochemical analysis of p-AKT in the colon tissues. (D) immunohistochemical analysis of p-NF-κB in the pancreas. (E) quantification of TLR4 levels in five different immunohistochemical images. (F) quantification of p-P3IK levels in five different immunohistochemical images. (G) quantification of p-AKT levels in five different immunohistochemical images. (H) quantification of p-NF-κB levels in five different immunohistochemical images. *P < 0.05, **P < 0.01 and ***P < 0.001 vs the UG group. n = 8 for each group.