Table 2.
Histopathology of COVID-19 in peer-reviewed English language journals.
| Date | First author (country) | Specimen type | No. of cases | Main findings | DAD | Thrombi |
|---|---|---|---|---|---|---|
| Feb 18, 2020 | Xu Z (China) (52) | Post-mortem biopsies of lung, liver, heart | 1 | DAD | Yes | None mentioned |
| Feb 28, 2020 | Tian S (China) (49) | Lobectomies | 2 | Edema, intra-alveolar fibrin, mononuclear inflammatory cells | Yes (“early DAD pattern” in 1 of 2) | None mentioned |
| April 10, 2020 | Barton LM (USA) (46) | Complete autopsies | 2 | DAD, chronic airway inflammation | Yes (1 case) | Few (lung, 1 case) |
| April 11, 2020 | Karami P (Iran) (47) | “Autopsy of lungs” | 1 | Hyaline membranes, viral cytopathic effect | Yes (hyaline membrane noted) | None mentioned |
| April 14, 2020 | Tian S (China) (50) | Post-mortem biopsies of lung, liver, heart | 4 | DAD | Yes | None mentioned |
| April 15, 2020 | Magro C (USA) (48) | Limited autopsies (2), skin biopsies (3) | 5 | “Hemorrhagic pneumonitis” (lung), “thrombogenic vasculopathy” (skin) | Yes (hyaline membranes in 1 of 2 cases in which lungs were examined) | Yes (skin) |
| April 16, 2020 | Barnes BJ (USA) (45) | Autopsies (brief mention) | 3 | “Neutrophil extracellular traps” | Not mentioned | Nonementioned |
| April 20, 2020 | Varga Z (Switzerland) (51) | Autopsies (2), small intestine resection (1) | 3 | Endotheliitis, DAD, viral inclusions in endothelial cells in kidney | Yes | “Only scattered fibrin thrombi” |
DAD, Diffuse alveolar damage.