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. 2020 Jul 29;11:1837. doi: 10.3389/fmicb.2020.01837

TABLE 6.

Relationship between antifungal susceptibility results and prognosis in 110 cryptococcal meningitis subjects.

Treatment regimen Total Survival (No. %) Dead (No. %) p-value
Amphotericin B containing regimen 84 64 (76.2) 20 (23.8) 0.588
WT 79 61 (77.2) 18 (22.8)
Non-WT 5 3 (60.0) 2 (40.0)
5-Flucytosine containing regimen 52 41 (78.8) 11 (21.2) 0.193
WT 48 39 (81.2) 9 (18.8)
Non-WT 4 2 (50) 2 (50)
Fluconazole containing regimen 57 44 (77.2) 13 (22.8) 0.034#
WT 53 43 (81.1) 10 (18.9)
Non-WT 4 1 (25.0) 3 (75.0)
Amphotericin B, fluconazole combined with 5-flucytosine 29 25 (86.2) 4 (13.8) 0.553
WT 24 21 (87.5) 3 (22.5)
Non-WT to any of amphotericin B, fluconazole, and 5-flucytosine 5 4 (80.0) 1 (20.0)
Amphotericin B combined with fluconazole 23 16 (69.6) 7 (30.4) 0.067
WT 19 15 (78.9) 4 (21.1)
Non-WT to amphotericin B or/and fluconazole 4 1 (25.0) 3 (75.0)
Amphotericin B combined with 5-flucytosine 21 16 (76.2) 5 (23.8) 0.429
WT 19 15 (78.9) 4 (21.1)
Non-WT to amphotericin B or/and 5-flucytosine 2 1 (50.0) 1 (50.0)
Fluconazole combined with 5-flucytosine 2 0 2 (100) /
WT 1 0 1 (100)
Non-WT to fluconazole or/and 5-flucytosine 1 0 1 (100)

WT, wild-type; Non-WT, non-wild-type. #p < 0.05.