Table 1.
Patient characteristics
| Variables | All patients (n = 413) | Without desmopressin (n = 85) | With desmopressin (n = 328) | P value |
|---|---|---|---|---|
| Age, yr | 61 (45–70) | 64 (51–69) | 60 (44–70) | 0.12 |
| Female | 187 (45) | 43 (51) | 144 (44) | 0.27 |
| Serum creatinine, mg/dl | 2.0 (1.2–3.4) | 1.4 (0.9–2.1) | 2.2 (1.3–3.6) | <0.001 |
| eGFR, ml/min per 1.73 m2 | 30 (16–62) | 45 (28–82) | 28 (15–51) | <0.001 |
| CKD stage | 0.002 | |||
| 1 (≥90) | 57 (14) | 17 (20) | 40 (12) | |
| 2 (60–89) | 52 (13) | 16 (19) | 36 (11) | |
| 3a (45–59) | 47 (11) | 10 (12) | 37 (11) | |
| 3b (30–44) | 68 (16) | 18 (21) | 50 (15) | |
| 4 (15–29) | 93 (23) | 15 (18) | 78 (24) | |
| 5 (<15) | 94 (23) | 8 (9) | 86 (26) | |
| AKI | 106 (26) | 16 (19) | 90 (27) | 0.13 |
| Proteinuria, g/d | 3.0 (1.0–6.0) | 3.0 (2.0–7.0) | 3.0 (1.0–6.0) | 0.11 |
| Hematuria | 198 (48) | 37 (44) | 161 (49) | 0.32 |
| Hypertension | 302 (73) | 63 (74) | 239 (73) | 0.81 |
| Elevated blood pressure before biopsy | 166 (40) | 37 (44) | 129 (39) | 0.46 |
| Hemoglobin, g/dl | 11.2 (9.7–12.9) | 11.7 (10.3–13.5) | 11.0 (9.6–12.7) | 0.004 |
| Platelet, ×109/l | 225 (179–283) | 224 (193–281) | 226 (171–285) | 0.40 |
| INR | 1.01 (0.95–1.08) | 1.01 (0.95–1.07) | 1.01 (0.95–1.08) | 0.68 |
| aPTT, s | 29.8 (27.4–32.3) | 29.6 (27.3–31.9) | 29.8 (27.3–32.3) | 0.57 |
AKI, acute kidney injury defined according to Kidney Disease: Improving Global Outcomes guidelines; aPTT, activated partial thromboplastin time; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate using Chronic Kidney Disease–Epidemiology Collaboration equation; INR, international normalized ratio.
Data are expressed as a median (interquartile range) or n (percent).