Table 2:

Effect of printing parameters on performance of DoE formulations (n=3).

Exp.	Shell Thicknes	Top/Bottom s Thickness	Infill Density	Rating force*	Dissolution 1h	Dissolution 4h	Dissolution 9h
	(mm)	(mm)	(%)	(μN)	(%)	(%)	(%)
N1	0.0	0.3	65	183 ± 31	22.9 ± 2.2	59 ± 4.0	94 ± 5.0
N2	0.8	0.3	65	96 ± 15	15.2 ± 1.7	42.2 ± 2.4	78.8 ± 4.1
N3	0.0	0.9	65	150 ± 25	19.7 ± 2.2	52.8 ± 1.9	89.5 ± 3.7
N4	0.8	0.9	65	24 ± 4	14.3 ± 1.3	40.3 ± 4.3	71.8 ± 3.0
N5	0.0	0.6	50	235 ± 25	22.3 ± 1.5	60 ± 2.2	95.7 ± 5.5
N6	0.8	0.6	50	99 ± 22	13.3 ± 1.1	41.6 ± 4.0	77.2 ± 3.7
N7	0.0	0.6	80	136 ± 29	17.0 ± 1.0	48.3 ± 2.4	84.4 ± 3.5
N8	0.8	0.6	80	18 ± 4	12.1 ± 1.0	37.2 ± 2.5	69.2 ± 3.0
N9	0.4	0.3	50	217 ± 36	16.6 ± 1.8	48.9 ± 2.1	85.8 ± 4.9
N10	0.4	0.9	50	100 ± 23	16.1 ± 1.7	45.3 ± 4.1	78.4 ± 4.3
N11	0.4	0.3	80	73 ± 16	14.2 ± 1.3	41.7 ± 3.7	75.1 ± 3.5
N12	0.4	0.9	80	49 ± 8	14.0 ± 1.3	40.6 ± 2.8	74.1 ± 3.9
N13	0.4	0.6	65	104 ± 26	15.7 ± 1.7	46.1 ± 3.6	81.3 ± 3.3
N14	0.4	0.6	65	113 ± 24	15.2 ± 1.1	45.8 ± 2.4	81.5 ± 4.1

^*Floating force was measured at 5 min after tablets was introduced to FaSSGF