Figure 4.
Adjusted spline analysis for the association between serum uric acid (SUA) and all-cause mortality in lean tissue index (LTI) and fat tissue index (FTI) subgroups. Subdistribution hazard ratios and confidence intervals across different SUA levels are displayed for patients with LTI at or below the median (12.4 kg/m2; blue) and LTI above the median (red) as well as for patients with FTI at or below the median (12.6 kg/m2; blue) and FTI above the median (red). Overlapping splines are displayed in the right plots (LTI/FTI at or below the median: dashed blue line indicates hazard ratios, and solid blue line indicates confidence intervals; LTI/FTI above the median: red line indicates hazard ratios, and light red lines indicate confidence intervals). Black bars indicate the number of patients for different SUA levels (Q1, first quartile; M, median; Q3, third quartile). Adjustment was performed for age, sex, ethnicity, dialysis vintage, comorbidities (diabetes mellitus, cardiovascular disease, liver disease, and cancer), vascular access, FTI (for LTI subgroups), and LTI (for FTI subgroups).