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. 2020 Aug 4;10:13149. doi: 10.1038/s41598-020-70174-z

Figure 1.

Figure 1

Microtubule Assembly in PD. Microtubule dynamics markers were determined in post-mortem human brain samples from SNpc, Hippocampus and Cortex of sporadic PD patients and controls. The levels of acetylated α-tubulin, acetylated tau, phosphor-tau and tau were determined in: (A) SNpc; (B) Hippocampus and (C) cortex brain tissue homogenates. (D) Densitometric analysis of the levels of acetylated α-tubulin, acetylated tau, phosphor-tau, tau and phosphor-tau/tau. The blots were re-probed for α-tubulin to confirm equal protein loading Values are mean ± SEM (n = 5, *p < 0.05, versus SNpc control subjects; &p < 0.05 and &&p < 0.01, versus cortex control subjects). Full length blots are presented in the Supplementary Information.