Table 1.
Positive correlations between levels of a range of presynaptic proteins in the basal forebrain (vertical diagonal band of Broca as a representative example) measured immunohistochemically in (A) wild-type mice or (B) tau transgenic L1 mice.
| A Wild-Type Mice | α-Synuclein | SNAP25 | Syntaxin | VAMP2 | Synaptophysin |
|---|---|---|---|---|---|
| α-Synuclein | |||||
| SNAP25 | * | ||||
| Syntaxin | ─ | ** | |||
| VAMP2 | ─ | * | * | ||
| Synaptophysin | ─ | ** | * | ─ | |
| Synapsin | ─ | ─ | ─ | ─ | ─ |
| B L1 Mice | α-Synuclein | SNAP25 | Syntaxin | VAMP2 | Synaptophysin |
| α-Synuclein | |||||
| SNAP25 | ─ | ||||
| Syntaxin | ─ | ─ | |||
| VAMP2 | ─ | ─ | ─ | ||
| Synaptophysin | ─ | ─ | ─ | * | |
| Synapsin | ─ | ─ | * | ─ | ─ |
Note: n = 9 per genotype. Significance of correlations, by linear regression analysis, are denoted as: *, p < 0.05; **, p < 0.01; ─, no significance at p = 0.05.