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. 2020 Jan;26(2):191–200. doi: 10.2174/1381612825666191216153508

Table 4.

Brain morphology changes in grey matter volume and white matter (WM) connectivity between schizophrenia (SZ) and bipolar disorder (BP).

Phenotype Morphology Volume/Connectivity Change Region
Schizophrenia Grey matter ↓↓ Insula
Grey matter ↓↓ Anterior cingulate cortex
Schizophrenia and Bipolar disorder Grey matter ↓↓ (SZ), ↓ (BP) Fronto-temporal cortex
Grey matter ↓↓ (SZ), ↓ (BP) Thalamus
Grey matter ↓↓ (SZ), ↓ (BP) Hippocampus
Grey matter ↓↓ (SZ), ↓ (BP) Amygdala
Schizophrenia White matter ↓↓ Fronto-temporal WM
Bipolar disorder White matter Left limbic WM
White matter Right temporal-parietal WM
Schizophrenia and Bipolar disorder White matter ↓↓ (SZ), ↓ (BP) Prefrontal WM
White matter ↓↓ (SZ), ↓ (BP) Cortico-thalamic WM
White matter ↓↓ (SZ), ↓ (BP) Callosal fiber