Skip to main content
letter
. 2020 Jun 24;10(2):e116. doi: 10.1002/ctm2.116

FIGURE 3.

FIGURE 3

Lnc‐CITED2‐2:1 might influence the GBC‐SD cell line function through regulating the protein expressions of CITED2 and key molecular of the EMT process. A, Western blot indicated that the knockdown of lnc‐CITED2‐2:1 decreased the expression level of E‐cadherin and increased the expression level of twist and vimentin. * P < .05; ** P < .01; *** P < .001. B, Western blot indicated that the overexpression of lnc‐CITED2‐2:1 increased the expression level of E‐cadherin and decreased the expression level of twist and vimentin. * P < .05; ** P < .01; *** P < .001. C, Western blot indicated that the overexpression of CITED2 in lnc‐CITED2‐2:1 overexpression GBC‐SD cell lines could promote the protein expression of twist and vimentin and suppress the protein expression of E‐cadherin. * P < .05; ** P < .01; *** P < .001. D, The overexpression of CITED2 in lnc‐CITED2‐2:1 overexpression GBC‐SD cell lines could inhibit the invasion ability of lnc‐CITED2‐2:1 overexpression GBC‐SD cells. * P < .05; ** P < .01; *** P < .001