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. 2020 Aug 4;6:24. doi: 10.1038/s41540-020-00142-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Percentage of protein sequence identity estimated using whole genome sequences of Candidatus Liberibacter asiaticus (CLas) strains and L. crescens BT-1. The identity between each CLas strain and BT-1 varied from 60–70%. b Protein-homology identity among CLas strains, which were over 99% identical. c Example of pathway completeness and gap filling for the TCA cycle and methionine metabolism in the CLas models. Circles represent metabolites, green represents gap filled reactions, and brown represents gene-associated reactions. d Reactions involved in central metabolism, including glycolysis/gluconeogenesis, the pentose phosphate pathway, and TCA cycle were categorized as pan reactions (highlighted in blue). The accessory reactions that include modeling reactions and other additional metabolic pathways (e.g., amino acid, carbohydrate and lipid metabolism) are shown in red. Unique reactions in each model are shown in orange.