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. 2020 Jul 9;13(4):21. doi: 10.3892/br.2020.1328

Figure 5.

Figure 5

Association between the expression of TOP2A, cancer type and HPV Infection Status in the 201291_s_at and 201292_at probes in the Zhai Cervix dataset. (A and B) TOP2A mRNA expression in CC between normal CC and precursor tissues. 0, no value (3); 1, cervix squamous epithelium (10); 2, cervical squamous cell carcinoma (21); 3, high grade cervical squamous intraepithelial neoplasia (7). (C and D) TOP2A mRNA expression and HPV Infection Status. 0, no value (3); 1, HPV negative (10); 2, HPV type 16 positive (14); 3, HPV type 18 positive (weak) (1); 4, HPV type 18 positive (4); 5, HPV type 18 and 45 positive (1); 6, HPV type 33 positive (1); 7, HPV type 33, 52 and 58 positive (4); 8, HPV type 56 positive (1); 9, HPV type 58 positive (1); 10, HPV type 59 positive (1). TOP2A, DNA topoisomerase II α; CC, cervical cancer; HPV, human papillomavirus. The numbers in the brackets refers to the number of samples.