Figure 6. Laboratory-confirmed dengue cases in intervention and control areas, before and after the Wolbachia intervention.

Dengue rapid diagnostic test results for patients presenting to primary care clinics in the intervention ( A) and control ( B) areas. Standard Diagnostics Dengue Duo rapid diagnostic kits for the detection of dengue virus NS1 antigen and IgM/IgG antibody were available in primary care clinics throughout Yogyakarta city from March 2016, and were used at the discretion of clinic staff as part of routine clinical care. Monthly counts of positive and negative results for DENV NS1 antigen, as recorded by clinic staff, were aggregated for all patients resident in the intervention area or control area. The blue dashed line indicates the completion of Wolbachia releases in the intervention area in March 2017.