Table 2.
Pre- and post-diagnosis annual mean all-cause hospitalization resource utilization and costs by severity of liver disease.
| Severity of liver disease | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| NAFLD/NASH overall (n = 125,052) |
CC (n = 1491) |
DCC (n = 7846) |
HCC (n = 1144) |
LT (n = 52) |
||||||
| Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | |
| Annual number of visits (n) | ||||||||||
| Mean (SD) | 2.4 (5.1) | 3.1 (5.6) | 2.8 (8.0) | 4.2 (8.6) | 4.7 (8.7) | 7.0 (11.1) | 3.0 (4.4) | 8.7 (10.3) | 11.6 (32.8) | 10.9 (24.6) |
| Median | 1.0 | 2.0 | 2.0 | 2.0 | 2.0 | 3.4 | 2.0 | 5.0 | 4.0 | 6.5 |
| 95% CI | 2.4 - 2.4 | 3.1 - 3.1 | 2.3 - 3.4 | 3.7 - 4.6 | 4.5 - 5.0 | 6.7 - 7.2 | 2.7 - 3.3 | 8.1 - 9.3 | 1.1 - 22.0 | 3.6 - 18.3 |
| Length per stay (days) | ||||||||||
| Mean (SD) | 2.7 (10.2) | 4.1 (7.4) | 3.2 (5.5) | 3.5 (5.6) | 5.2 (16.6) | 9.1 (15.4) | 3.8 (13.6) | 5.6 (6.3) | 5.2 (10.1) | 9.0 (7.6) |
| Median | 1.0 | 3.0 | 1.5 | 2.0 | 3.0 | 6.1 | 1.7 | 4.0 | 2.8 | 6.5 |
| 95% CI | 2.6 - 2.8 | 4.0 - 4.1 | 2.8 - 3.5 | 3.2 - 3.8 | 4.8 - 5.7 | 8.7 - 9.4 | 2.8 - 4.7 | 5.2 - 6.0 | 2.0 - 8.5 | 6.7 - 11.2 |
| Annual cost per patient (€) | ||||||||||
| Mean (SD) | 5075.9 (8387.8) | 7736.3 (13,870.1) | 5828.2 (7933.9) | 10,001.5 (19,933.3) | 11,892.0 (14,864.6) | 25,620.6 (35,101.6) | 7241.0 (8882.3) | 26,171.7 (23,461.5) | 19,844.4 (25,363.5) | 82,978.5 (64,774.0) |
| Median | 2482.8 | 4121.3 | 3252.2 | 4468.9 | 6711.2 | 14,109.9 | 4405.8 | 19,422.8 | 9478.2 | 61,534.3 |
| 95% CI | 5001.7 - 5150.2 | 7659.2 - 7813.5 | 5283.0 - 6373.4 | 8980.6 - 11,022.4 | 11,475.1 - 12,308.9 | 24,806.0 - 26,435.3 | 6602.1 - 7879.8 | 24,762.4 - 27,581.0 | 11,732.7 - 27,956.0 | 63,743.0 - 102,214.0 |
CC, compensated cirrhosis; DCC, decompensated cirrhosis; HCC, hepatocellular carcinoma; LT, liver transplantation; NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis; CI, confidence interval; SD, standard deviation.