Figure 2.

LGR6 Promotes Tumorigenesis in TNBC

(A) LGR6 expression was confirmed by quantitative real-time PCR in LGR6 stable expressing/knockdown cells, and β-actin was used as a loading control. (B) Cell proliferation assays were conducted to compare the cell growth rates between LGR6-MDA-MB-468 and control cells and between shLGR6-BT549 and control cells. (C) Representative images of xenografts and a summary of tumor weight in nude mice. The weights of xenograft tumors are summarized in the right panel. All results are expressed as the mean ± standard deviation of three independent experiments (∗p < 0.05).