Table 3.
Tabulated data on rates of 67Cu loss in rats where the common bile duct was and was not (sham) ligated prior to 67Cu administration. Reprinted with permission from Linder, M.C. et al. [2].
| Sham-Operated Controls | Bile Duct Ligation | |
|---|---|---|
| Slope [Means ± SD (N)] * 0–63 h 0–86 h |
−552 ± 28 (23) −623 ± 56 (28) |
−258 ± 97 (15) ** −272 ± 67 (17) *** |
| Half-life (h) 0–63 h 0–86 h |
54 h 49 h |
117 h 110 h |
| Liver [Means ± SD (N)] Cu (ug/g) 67Cu specific activity (cpm/ug) |
4.6 ± 0.5 (6) 64 ± 11 (4) |
3.8 ± 1.1 (6) 105 ± 42 (5) |
* Multiplied by 106. ** p < 0.01, *** p < 0.001.