Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 21;21(14):5168. doi: 10.3390/ijms21145168

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The intracellular signalling of endothelial cells upon ligation of fibrinogen (and iD-dimer): adapted from [70,71,72,73,75,100,102]. Abbreviations: ICAM-1, intercellular adhesion molecule-1; RhoA, activated Rho factor protein; iD-dimer, immobilised D-dimer; ROS, reactive oxygen species; Src, sarcoma; MEKK316, endothelial MAP kinases 3 and 6 (MKK-3 and -6); FAK, focal adhesion kinase; p130, retinoblastoma-like protein-2; p38, mitogen-activated protein kinase; HSP27, heat shock protein 27; ERK, extracellular signal-regulated kinase/extracellular receptor kinase; c-Fos, proto-oncogene; JNK, stress-activated protein kinase; c-Jun, protein encoded by the JUN gene; VCAM-1, vascular cell adhesion protein-1; IL-8, interleukin-8; RANTES, regulated upon activation normal T cell expressed and presumably secreted; IL-1 beta, interleukin-1 beta. This image was made with BioRender (https://biorender.com/).