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. 2020 Jul 15;21(14):5009. doi: 10.3390/ijms21145009
ACT Adoptive cellular therapy
APC Antigen presenting cell
CAR Chimeric antigen receptor
CDK Cyclin-dependent kinase
CI Confidence interval
CML Chronic myeloid leukemia
CRISPR Clustered regularly interspaced short palindromic repeats
CTL Cytotoxic T-lymphocyte
CTLA-4 Cytotoxic T-lymphocyte-associated protein 4
DC Dendritic cell
DNA Deoxyribonucleic acid
FasL Fas ligand
HLA Human leukocyte antigen
ICI Immune checkpoint inhibitor
IFN Interferon
Ig Immunoglobulin
IL Interleukin
ITIM Immunoreceptor tyrosine-based inhibition motif
LAG-3 Lymphocyte activation gene 3 protein
LFT Liver function test
mAbs Monoclonal antibodies
MHC Major histocompatibility complex
NF-kB Nuclear factor kB
NHL Non-Hodgkin’s lymphoma
NK Natural killer
NSCLC Non-small cell lung cancer
OS Overall survival
pCR Pathologic complete response rates
PD-1 Programmed cell death protein 1
PD-L1 Programmed death-ligand 1
PFS Progression free survival
RCC Renal cell carcinoma
TCR T cell receptor
TGF Transforming growth factor
TIL Tumor infiltrating lymphocyte
TIM-3 T cell Ig mucin domain-containing 3
TME Tumor microenvironment
TNBC Triple negative breast cancer
TNF Tumor necrosis factor
TNFR Tumor necrosis factor receptor
TNFRSF4 Tumor necrosis factor receptor superfamily member 4
TRAEs Treatment-related adverse effects
Treg Regulatory T cell
VEGF Vascular endothelial growth factor
VEGFR Vascular endothelial growth factor receptor
VISTA V-domain Ig suppressor of t-cell activation