ACT |
Adoptive cellular therapy |
APC |
Antigen presenting cell |
CAR |
Chimeric antigen receptor |
CDK |
Cyclin-dependent kinase |
CI |
Confidence interval |
CML |
Chronic myeloid leukemia |
CRISPR |
Clustered regularly interspaced short palindromic repeats |
CTL |
Cytotoxic T-lymphocyte |
CTLA-4 |
Cytotoxic T-lymphocyte-associated protein 4 |
DC |
Dendritic cell |
DNA |
Deoxyribonucleic acid |
FasL |
Fas ligand |
HLA |
Human leukocyte antigen |
ICI |
Immune checkpoint inhibitor |
IFN |
Interferon |
Ig |
Immunoglobulin |
IL |
Interleukin |
ITIM |
Immunoreceptor tyrosine-based inhibition motif |
LAG-3 |
Lymphocyte activation gene 3 protein |
LFT |
Liver function test |
mAbs |
Monoclonal antibodies |
MHC |
Major histocompatibility complex |
NF-kB |
Nuclear factor kB |
NHL |
Non-Hodgkin’s lymphoma |
NK |
Natural killer |
NSCLC |
Non-small cell lung cancer |
OS |
Overall survival |
pCR |
Pathologic complete response rates |
PD-1 |
Programmed cell death protein 1 |
PD-L1 |
Programmed death-ligand 1 |
PFS |
Progression free survival |
RCC |
Renal cell carcinoma |
TCR |
T cell receptor |
TGF |
Transforming growth factor |
TIL |
Tumor infiltrating lymphocyte |
TIM-3 |
T cell Ig mucin domain-containing 3 |
TME |
Tumor microenvironment |
TNBC |
Triple negative breast cancer |
TNF |
Tumor necrosis factor |
TNFR |
Tumor necrosis factor receptor |
TNFRSF4 |
Tumor necrosis factor receptor superfamily member 4 |
TRAEs |
Treatment-related adverse effects |
Treg |
Regulatory T cell |
VEGF |
Vascular endothelial growth factor |
VEGFR |
Vascular endothelial growth factor receptor |
VISTA |
V-domain Ig suppressor of t-cell activation |