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. 2020 Jul 19;21(14):5103. doi: 10.3390/ijms21145103

Figure 2.

Figure 2

Inhibition of C. acnes growth and MIP-2 production by PEG-8 Laurate fermentation of S. epidermidis in vivo. The ears of ICR mice were intradermally injected with C. acnes (107 CFU) and S. epidermidis (S. epi), (107 CFU) with 2% PEG-8 Laurate or H2O. Ear morphology 5 d after injection (a) and changes in ear thickness (mm) (b) were shown. Scale bar = 1 mm. (c) The CFUs (Log10 CFU/mL) were assessed by enumerating plating serial dilution (1:100–1:105) of the ear homogenates on agar plates. (d) The levels of MIP-2 cytokines in ear homogenates were measured by ELISA. Data are represented as mean ± SD of three separate experiments, using three mice per group. *** p < 0.001 (two-tailed t-tests).