Figure 4.

Enhancement of anti-C. acnes activity and reduction of required doses of clindamycin by PEG-8 fermentation of S. epidermidis in an overlay assay. (a) C. acnes (10⁶ CFU) in the presence or absence of 1 or 0.1% clindamycin (CDM) was overlaid on top of a lawn of S. epidermidis (10⁸ CFU), with or without 2% PEG-8 Laurate. Scale bar = 1 cm (b) Graphical presentation of quantification of area (arbitrary unit, a.u.) of a C. acnes colony. Results display as mean ± SD in triplicate. ** p < 0.05 (two-tailed t-tests); ns = non-significant.