Figure 8.
Effect of Hydrogel treatment on iNOS levels. By immunohistochemical analysis, it turned out that the level of iNOS was increased in mice of vehicle groups that received IMQ treatment (B magnification 20×, B1 magnification 40×, D,E,E1) compared to the sham-operated mice (A magnification 20×, A1 magnification 40×, D,E,E1). Moreover, Hydrogel treatment significantly decreased iNOS levels (C magnification 20×, C1 magnification 40×, D,E,E1). Data are representative of at least three independent experiments; One-Way ANOVA test. *** p < 0.001 vs. sham; ### p < 0.001 vs. IMQ.