Table 1.

Expression of P2 receptors within the cells of the distal lung.

Cell Type	P2 Receptor	Expression
ATI	P2X7	mRNA (r [27]), protein (r [27])
	P2Y2	protein (r [28])
ATI like	P2Y2	protein (h [28], r [28])
ATII	P2X4	mRNA (r [29,30]), protein (r [29,30])
	(P2X7)	mRNA (r [30]), protein (r [30])
	P2Y2	mRNA (r [30,31]), protein (r [30])
	P2Y6	mRNA (r [30]), protein (r [30])
EC	P2X1	mRNA (h [32]), protein (h [32])
	P2X4	mRNA (h [32,33,34,35]), protein (h [32])
	P2X5	mRNA (h [32,34,35]), protein (h [32])
	P2X6	mRNA (h [35])
	P2X7	mRNA (h [35])
	P2Y1	mRNA (h [32,35,36,37]), protein (h [32,36])
	P2Y2	mRNA (h [35,37])
	P2Y6	mRNA (h [32]), protein (h [32])
	P2Y11	mRNA (h [32,36,37,38]), protein (h [32,36])
	P2Y12	mRNA (h [37])
	P2Y14	mRNA (h [37])
Fibroblasts	P2Y2	mRNA (h [39])
	P2Y4	mRNA (h [39])
	P2Y6	mRNA (h [39])
	P2Y11	mRNA (h [39])
Alveolar macrophages	P2X1	mRNA (h [40], m [41], r [42])
	P2X3	mRNA (m [41] h [40])
	P2X4	mRNA (h [40], m [41], r [42]), protein (h [43], r [43,44]),
	P2X5	mRNA (h [40])
	P2X7	mRNA (h [40], r [42])
	P2Y1	mRNA (h [40], r [42])
	P2Y2	mRNA (h [40], r [42])
	P2Y4	mRNA (h [40], r [42])
	P2Y6	mRNA (h [40])
	P2Y11	mRNA (h [40])
	P2Y12	mRNA (r [42])
	P2Y13	mRNA (h [40])
	P2Y14	mRNA (h [40])
Neutrophils	P2X1	mRNA (h [45,46,47], r [48]), protein (h [47])
	P2X4	mRNA (h [46,47], r [48])
	P2X5	mRNA (h [45,46,47], r [48])
	P2X6	mRNA (h [47])
	P2X7	ambiguous data ([45,46,48,49,50,51,52])
	P2Y1	mRNA (h [46])
	P2Y2	mRNA (h [46,51,53]), protein (h [51], r [48])
	P2Y4	mRNA (h [51])
	P2Y6	mRNA (h [51])
	P2Y11	mRNA (h [51]), protein (h [45], r [48])
	P2Y14	mRNA (h [54])

The table summarizes the evidence for P2 receptor expression in the distal lung that has been reported at the mRNA and protein level in human (h), mouse (m) and rat (r).