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. 2020 Jul 8;21(14):4822. doi: 10.3390/ijms21144822

Figure 2.

Figure 2

mRNA expression of CYP27A1 and CYP7B1 in different subtypes of breast cancer. (a) The expression level of CYP27A1 is significantly upregulated in TNBC compared to normal tissues (p-value < 10−6), while it is not different in ER-positive or HER2-positive group compared to the normal group (p-value > 0.5). (b) CYP7B1 mRNA expression is significantly lower in both luminal (p-value < 10−11) and HER2-positive (p-value < 10−5) tumor groups compared to normal breast tissues, while it is not different in TNBC compared to normal tissues (p-value > 0.5). The expression data are based on the TCGA data and visualized by the UALCAN portal [69].