| °C | Degrees Celsius (temperature) |
| aa | amino acid |
| ACTB | beta-actin |
| Adnp | Activity-Dependent Neuroprotector Homeobox Protein |
| ALS | Amyotrophic Lateral Sclerosis |
| ANOVA | Analysis of variance |
| ARHGEF11 | Rho Guanine Nucleotide Exchange Factor (GEF) 11 |
| ATF1 | Activating Transcription Factor 1 |
| ATG | Start codon Adenine-Thymidine/Uracil-Guanine |
| ATX-2 | the single nematode ortholog of mammalian Ataxin-2 and Ataxin-2-like |
| ATXN2 | Ataxin-2 |
| ATXN2L | Ataxin-2-like, aka: Ataxin-2-Related Protein, A2LP, A2RP or A2D |
| BDNF | Brain-Derived Neurotrophic Factor |
| bp | Base pair |
| BSA | Bovine serum albumin |
| Carm1 | Coactivator Associated Arginine Methyltransferase 1 |
| Cart1 | Cartilage paired class homeoprotein 1 (aka Alx1) |
| Cb | Cerebellum |
| Cbp | cAMP-response element binding protein (Creb) binding protein (aka Crebbp) |
| cDNA | complementary Deoxyribo-Nucleic Acid |
| CID3 | CTC-interacting domain 3 protein in Arabidopsis thaliana |
| CID4 | CTC-interacting domain 4 protein in Arabidopsis thaliana |
| Cited2 | Cbp/P300 Interacting Transactivator With Glu/Asp Rich Carboxy-Terminal Domain 2 |
| Crispr/Cas9 | Clustered Regularly Interspaced Short Palindromic Repeats/Crispr-associated protein 9 |
| C-term | C-terminal end of the protein |
| Ctx | Cortex |
| DAPK1 | Death-Associated Protein Kinase 1 |
| DDX6 | DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 6 (RNA Helicase, 54kD) |
| DENND1A | DENN/MADD Domain Containing 1A (RAB35-activating guanine nucleotide exchange factor) |
| DMEM | Dulbecco’s modified essential medium |
| DNA | Desoxyribo-Nucleic-Acid chain |
| E | Embryonic development day |
| E2F1 | E2F Transcription Factor 1 |
| e.g., | Exemplo gratia (for example, in Latin language) |
| EGF | Epidermal growth factor |
| ELF1 | E74 Like ETS Transcription Factor 1 |
| Ep300 | E1A Binding Protein, Histone Acetyltransferase P300 |
| EST | Expressed sequence tag |
| Ex1 | Exon 1 |
| FCS | Fetal calf serum |
| FTLD | Fronto-temporal lobar dementia |
| Foxj2 | Forkhead Box Protein J2, a transcriptional activator |
| g | Gram |
| G3BP2 | Ras-GTPase Activating Protein SH3 Domain-Binding Protein 2 |
| GLAST GWAS |
Sodium-Dependent Glutamate/Aspartate Transporter 1 (in astrocytes) Genome wide association studies |
| h | hour |
| H&E | Hematoxylin and Eosin staining |
| HBSS | Hank’s buffered salt solution |
| Het | Heterozygote |
| HNRNP | Heterogeneous Nuclear Ribonucleoprotein |
| Kb | kilo-base |
| IRF1 | Interferon Regulatory Factor 1 |
| ITS | Insulin-Transferrin-Selenium |
| KD | Knock-Down |
| KO | Knock-Out |
| L | liter |
| lncRNA | long non-coding RNA |
| Lsm | Like “Smith antigen” protein domain |
| LSM12 | Homolog of yeast cytosolic LSM12 protein |
| LsmAD | Lsm-associated domain |
| mg | milliGram |
| mm | milliMeter |
| mM | milliMolar |
| µg | microGram |
| µL | microLiter |
| µM | microMolar |
| MEF | Mouse embryonal fibroblasts |
| MEM | Minimal Essential Medium |
| MGI mGluR5 |
Mouse Genome Informatics metabotropic Glutamate Receptor 5 |
| MPL | Interactor domain with Myelo-Proliferative Leukemia gene, encodes Thrombopoietin receptor |
| mRNA | Messenger ribonucleic acid |
| mTORC1 | Mechanistic “target of rapamycin” complex 1 |
| Neat1 | Nuclear Paraspeckle Assembly Transcript 1 |
| NFATC2IP | Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein |
| ng | nanoGram |
| NHGRI-EBI N-term |
American National Human Genetics Research Institute & European Bioinformatics Institute N-terminal end of the protein |
| NUFIP2 | Nuclear Fragile X Mental Retardation Protein 1 Interacting Protein 2 |
| ORF | open reading frame |
| p | probability value for the occurrence of a given observation by chance |
| PABPC1 | Poly(A)-binding-protein cytosolic 1 |
| PAM2 | Poly(A)-binding mediator domain 2 |
| PBS | Phosphate buffered saline |
| PFA | Paraformaldehyde |
| poly(A) tail | adenosine-repeat at the 3′ end of mRNA |
| Poly(I:C) | Poly-Inosinic: Poly-Cytidylic acid chain |
| Pro | Proline |
| PRD | Proline-rich domain |
| PSD-95 PSP |
Postsynaptic Density Protein 95 (aka DLK4, Disks Large Homolog 4) progressive supranuclear palsy (aka Parkinson plus) |
| Q, 22Q | glutamine, repeat of 22 consecutive glutamines |
| RA | Retinoic acid |
| RT-qPCR | Reverse-Transcriptase quantitative Polymerase Chain Reaction |
| S6R | Small ribosomal subunit protein 6 |
| SCA1 | Spinocerebellar Ataxia type 1 |
| SCA2 | Spinocerebellar Ataxia type 2 |
| SDS | Sodium-Dodecyl-Sulfate detergent |
| s.e.m. | Standard error of the mean |
| Setd5 | Histone-Lysine N-Methyltransferase, SET domain containing 5 |
| SG | Stress granule |
| sgRNA | Single guide Ribo-Nucleic-Acid chain |
| Sh2b1 | Pro-Rich, PH And SH2 Domain-Containing Signaling Mediator gene |
| SH3 | Src-homology 3 domain |
| SH-SY5Y | Cell line subcloned from SK-N-SH line from 4-year-old female neuroblastoma patient |
| SITE+3 | Selenite, Insulin, Transferrin, Ethanolamine +3 |
| SLC9A3R2 SNP |
Solute Carrier Family 9 (Sodium/Hydrogen Exchange) Member 3 Regulator 2 (aka NHERF2) Single nucleotide polymorphism |
| SPITE | Selenite, Pyruvate, Insulin, Transferrin, Ethanolamine +3 |
| SR-B1 Src |
Scavenger Receptor Class B Member 1 (aka CD36, Thrombospondin Receptor-Like 1) V-Src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene |
| Tbp | TATA-binding factor of transcription |
| TDP-43 | TAR (transcription active response element) DNA-Binding Protein 43 (encoded by TARDBP) |
| Tfap2a | Transcription Factor Activator-Protein-2 alpha |
| TIGM, TX | Texas Institute of Genomic Medicine, Texas, United States of America |
| TPM | Transcripts per million (expression unit as normalization method in RNA-sequencing) |
| Tufm | Tu Translation Elongation Factor, Mitochondrial gene |
| ULK1 | Unc-51 Like Autophagy Activating Kinase 1 |
| VPS54 | Vacuolar Protein Sorting-Associated Protein 54 (endosomal factor for retrograde transport) |
| WT | Wild-Type |