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. 2020 Jul 20;21(14):5124. doi: 10.3390/ijms21145124
°C Degrees Celsius (temperature)
aa amino acid
ACTB beta-actin
Adnp Activity-Dependent Neuroprotector Homeobox Protein
ALS Amyotrophic Lateral Sclerosis
ANOVA Analysis of variance
ARHGEF11 Rho Guanine Nucleotide Exchange Factor (GEF) 11
ATF1 Activating Transcription Factor 1
ATG Start codon Adenine-Thymidine/Uracil-Guanine
ATX-2 the single nematode ortholog of mammalian Ataxin-2 and Ataxin-2-like
ATXN2 Ataxin-2
ATXN2L Ataxin-2-like, aka: Ataxin-2-Related Protein, A2LP, A2RP or A2D
BDNF Brain-Derived Neurotrophic Factor
bp Base pair
BSA Bovine serum albumin
Carm1 Coactivator Associated Arginine Methyltransferase 1
Cart1 Cartilage paired class homeoprotein 1 (aka Alx1)
Cb Cerebellum
Cbp cAMP-response element binding protein (Creb) binding protein (aka Crebbp)
cDNA complementary Deoxyribo-Nucleic Acid
CID3 CTC-interacting domain 3 protein in Arabidopsis thaliana
CID4 CTC-interacting domain 4 protein in Arabidopsis thaliana
Cited2 Cbp/P300 Interacting Transactivator With Glu/Asp Rich Carboxy-Terminal Domain 2
Crispr/Cas9 Clustered Regularly Interspaced Short Palindromic Repeats/Crispr-associated protein 9
C-term C-terminal end of the protein
Ctx Cortex
DAPK1 Death-Associated Protein Kinase 1
DDX6 DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 6 (RNA Helicase, 54kD)
DENND1A DENN/MADD Domain Containing 1A (RAB35-activating guanine nucleotide exchange factor)
DMEM Dulbecco’s modified essential medium
DNA Desoxyribo-Nucleic-Acid chain
E Embryonic development day
E2F1 E2F Transcription Factor 1
e.g., Exemplo gratia (for example, in Latin language)
EGF Epidermal growth factor
ELF1 E74 Like ETS Transcription Factor 1
Ep300 E1A Binding Protein, Histone Acetyltransferase P300
EST Expressed sequence tag
Ex1 Exon 1
FCS Fetal calf serum
FTLD Fronto-temporal lobar dementia
Foxj2 Forkhead Box Protein J2, a transcriptional activator
g Gram
G3BP2 Ras-GTPase Activating Protein SH3 Domain-Binding Protein 2
GLAST
GWAS
Sodium-Dependent Glutamate/Aspartate Transporter 1 (in astrocytes)
Genome wide association studies
h hour
H&E Hematoxylin and Eosin staining
HBSS Hank’s buffered salt solution
Het Heterozygote
HNRNP Heterogeneous Nuclear Ribonucleoprotein
Kb kilo-base
IRF1 Interferon Regulatory Factor 1
ITS Insulin-Transferrin-Selenium
KD Knock-Down
KO Knock-Out
L liter
lncRNA long non-coding RNA
Lsm Like “Smith antigen” protein domain
LSM12 Homolog of yeast cytosolic LSM12 protein
LsmAD Lsm-associated domain
mg milliGram
mm milliMeter
mM milliMolar
µg microGram
µL microLiter
µM microMolar
MEF Mouse embryonal fibroblasts
MEM Minimal Essential Medium
MGI
mGluR5
Mouse Genome Informatics
metabotropic Glutamate Receptor 5
MPL Interactor domain with Myelo-Proliferative Leukemia gene, encodes Thrombopoietin receptor
mRNA Messenger ribonucleic acid
mTORC1 Mechanistic “target of rapamycin” complex 1
Neat1 Nuclear Paraspeckle Assembly Transcript 1
NFATC2IP Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein
ng nanoGram
NHGRI-EBI
N-term
American National Human Genetics Research Institute & European Bioinformatics Institute
N-terminal end of the protein
NUFIP2 Nuclear Fragile X Mental Retardation Protein 1 Interacting Protein 2
ORF open reading frame
p probability value for the occurrence of a given observation by chance
PABPC1 Poly(A)-binding-protein cytosolic 1
PAM2 Poly(A)-binding mediator domain 2
PBS Phosphate buffered saline
PFA Paraformaldehyde
poly(A) tail adenosine-repeat at the 3′ end of mRNA
Poly(I:C) Poly-Inosinic: Poly-Cytidylic acid chain
Pro Proline
PRD Proline-rich domain
PSD-95
PSP
Postsynaptic Density Protein 95 (aka DLK4, Disks Large Homolog 4)
progressive supranuclear palsy (aka Parkinson plus)
Q, 22Q glutamine, repeat of 22 consecutive glutamines
RA Retinoic acid
RT-qPCR Reverse-Transcriptase quantitative Polymerase Chain Reaction
S6R Small ribosomal subunit protein 6
SCA1 Spinocerebellar Ataxia type 1
SCA2 Spinocerebellar Ataxia type 2
SDS Sodium-Dodecyl-Sulfate detergent
s.e.m. Standard error of the mean
Setd5 Histone-Lysine N-Methyltransferase, SET domain containing 5
SG Stress granule
sgRNA Single guide Ribo-Nucleic-Acid chain
Sh2b1 Pro-Rich, PH And SH2 Domain-Containing Signaling Mediator gene
SH3 Src-homology 3 domain
SH-SY5Y Cell line subcloned from SK-N-SH line from 4-year-old female neuroblastoma patient
SITE+3 Selenite, Insulin, Transferrin, Ethanolamine +3
SLC9A3R2
SNP
Solute Carrier Family 9 (Sodium/Hydrogen Exchange) Member 3 Regulator 2 (aka NHERF2)
Single nucleotide polymorphism
SPITE Selenite, Pyruvate, Insulin, Transferrin, Ethanolamine +3
SR-B1
Src
Scavenger Receptor Class B Member 1 (aka CD36, Thrombospondin Receptor-Like 1)
V-Src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene
Tbp TATA-binding factor of transcription
TDP-43 TAR (transcription active response element) DNA-Binding Protein 43 (encoded by TARDBP)
Tfap2a Transcription Factor Activator-Protein-2 alpha
TIGM, TX Texas Institute of Genomic Medicine, Texas, United States of America
TPM Transcripts per million (expression unit as normalization method in RNA-sequencing)
Tufm Tu Translation Elongation Factor, Mitochondrial gene
ULK1 Unc-51 Like Autophagy Activating Kinase 1
VPS54 Vacuolar Protein Sorting-Associated Protein 54 (endosomal factor for retrograde transport)
WT Wild-Type