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. 2020 Jul 15;21(14):4995. doi: 10.3390/ijms21144995

Figure 2.

Figure 2

Regulation of mTORC, especially related to amino acids and signals of growth factors. IRS: insulin receptor substrate, PI3K: phosphoinositide 3-kinase, PIP2: phosphatidylinositol-4, 5-bisphosphate, PETN: phosphatase and tensin homolog, mTORC: mTOR complex, MAPK: Mitogen-activated Protein Kinase, RSK: ribosomal protein S6 kinase, TSC: tuberous sclerosis complex, Dotted arrow; abridged signaling factors, In table, +: presence, −: absence.