Figure 2.
Regulation of mTORC, especially related to amino acids and signals of growth factors. IRS: insulin receptor substrate, PI3K: phosphoinositide 3-kinase, PIP2: phosphatidylinositol-4, 5-bisphosphate, PETN: phosphatase and tensin homolog, mTORC: mTOR complex, MAPK: Mitogen-activated Protein Kinase, RSK: ribosomal protein S6 kinase, TSC: tuberous sclerosis complex, Dotted arrow; abridged signaling factors, In table, +: presence, −: absence.