Figure 3.

Fragmented DNA stabilizes tryptase activity. β-tryptase (0.07 µg) was incubated at room temperature (A,B) or 37 °C (C,D) in the absence or presence of either heparin, intact dsDNA or fragmented dsDNA of the indicated sizes. Residual tryptase activity was then measured using the chromogenic substrate S-2288. The data are representative of at least 3 individual experiments. Data are given as mean values ± SD (n = 3) *** p ≤ 0.001 **** p ≤ 0.0001 (Unpaired t-test).