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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Resveratrol counteracted the free fatty acid (FFA)/palmitate-induced muscle cell insulin resistance. Resveratrol prevented the FFA-induced serine phosphorylation of IRS-1 and phosphorylation/activation of mTOR and p70 S6K, and increased the activation of AMPK.