Table 2.

Total integrated discrimination index (IDI) and net reclassification index (NRI) for adding fasting brain-derived neurotrophic factor (BDNF), BDNF at 30 min, and area under the curve (AUC) of BDNF to Framingham risk score (FRS) to predict the cardiovascular events.

Model	IDI (95% CI)	p	NRI (95% CI)	p
Model 1	Reference		Reference
Model 2	−0.001 (−0.004, 0.021)	0.163	−0.027 (−0.234, 0.158)	0.751
Model 3	0.039 (0.004, 0.131)	0.013	0.393 (0.001, 0.548)	0.040
Model 4	0.039 (0.006, 0.123)	0.007	0.451 (0.062, 0.610)	0.027

Model 1 = FRS alone, Model 2 = fasting BDNF + FRS, Model 3 = BDNF at 30 min + FRS, and Model 4 = AUC of BDNF + FRS, CI = confidence interval.